The A4541 was a short A-road to the east of Shrewsbury town centre, forming the start of an eastern bypass for the town.
The road started at Meole Brace at a roundabout on the A5 (now B4380) and A49 and headed northeastwards along Hazledine Way. After crossing the Shrewsbury to Hereford railway line and the Rea Brook it bore right to reach The Column, where it ended at another roundabout on the A458 and A5112.
The road was built in the 1970s but the A4541 number was short-lived. It was soon renumbered as an extension of the A5112 which continued along the eastern bypass to reach the A49 at Ditherington; a short section at the northern end was left which is now part of the A458. It is in fact debatable whether the A4541 number was out-of-zone in the first place: the entire road was the wrong side of the A5 Shrewsbury bypass but the right side of the original line of the A5.