The A2021 is a link road between the A2270 (the former A22) and the north of Eastbourne, seemingly dating to 1935. It runs mostly parallel to the A2270 for most of its length.
Halfway along is a roundabout that serves as the entrance to Eastbourne District General Hospital and as the terminus of the A2280 Cross Levels Way. The latter road is the continuation of the new route into Eastbourne of the A22, which terminates at the Lottbridge Roundabout, about a mile away to the north-east. All traffic heading for Eastbourne then follows the A2021 south-eastward along King's Drive and Lewes Road. Just before we cross the railway line, the A2040 Upper Avenue turns off to the right for the town centre and the A2021 continues over the railway as Whitley Road before ending on the A259, Seaside, at a T-junction.