The B280 is a short B-road on the southern edge of Greater London.
Originally it started on the B272 to the west of Purley and headed west along a road that was renumbered A2022 in the 1970s. The original B280 went through Banstead but this was bypassed in the 1930s; it appears to have been numbered B2217 since then.
The eastern end of the B280 is now at a set of traffic lights on the A24 one-way system in Epsom. It heads west to cross a finger of the Royal Borough of Kingston upon Thames, where it crosses the A243 at Malden Rushett, just to the south of Chessington World of Adventures, again by traffic lights.
This was the original western end of the B280 but it was extended in the 1940s through Prince's Coverts to enter Oxshott and terminate at traffic lights on the A244.