This article is about the Class III road numbered C645 maintained by DfI Roads. For other roads numbered C645, see C645.
The C645 starts on the A45 at the southern edge of Dungannon and heads south through the village of Moygashiel and crosses the A4 dual carriageway via a pair of LILO junctions. To the west of Moy the road comes to a crossroads from which it continues both west and east. To the west the road leads to the B130 while to the east the road heads towards Moy where it terminates at a TOTSO on the B106.