The A5250 is a road in Derby, linking the A5111 Outer Ring Road to the A601 Inner Ring Road. Some maps show it starting further southwest, at a GSJ on the A38 north of Findern. This is incorrect and Derby City Council's network list shows the correct starting point is the Outer Ring Road.
The A5250 begins at a large, traffic-signal-controlled junction on the A5111, which is often fairly busy during rush hour. From here it heads northeastward towards the city centre via a somewhat hilly route. The main A5250 ends at the Burton Road roundabout on the A601. However, close to the city centre, a number of other streets are classified on some maps as the A5250, despite now carrying very little traffic indeed. This is due to their former use as part of the inner ring road before completion of the A601. These are Mount Street, Mill Hill Lane, a section of Normanton Road, Charnwood Street and Leopold Street.
The A5250 follows the former course of the A38 into Derby. It came into being (presumably) when the A38 was diverted along the Mickleover Bypass in the early 1970s. Both the A50 and the A52 run near to or through Derby; however, it is unclear whether this had any bearing on the selection of the number (neither route meets this road) or was just a pleasing coincidence.