The A5189 is a short road passing to the south of Burton upon Trent town centre.
The road starts at a roundabout where it meets the A5121 and B5017. Heading east, it multiplexes with the latter over the railway line before it turns off at the next roundabout. We then skirt the town centre and have another short multiplex between two roundabouts, this time with the B5018. After passing Tesco the road crosses the River Trent on St Peter's Bridge and ends on the far side at a roundabout on the A444.