It starts at a set of traffic lights where the A310 bends just to the north of Twickenham station and the bridge over the River Crane. It heads northwest, crossing the A316 at a roundabout shortly afterwards. At a set of traffic lights one block north it TOTSOs left and runs past Twickenham stadium.
The B361 crosses a bridge over the Duke of Northumberland's River before having to TOTSO right along Kneller Road. Behind the wall on the right is the Royal Military School of Music (still part of the Army hence the security); the entrance is passed a short distance later.
The B361 TOTSOs right at a T-junction adjacent to St Philip & St James' Church before continuing north along Whitton Road to cross a railway line by Hounslow station. The road ends a short distance later at a set of traffic lights on the A314 in the centre of Hounslow.