|Via:||Warrington, Leeds, Doncaster|
|Length:||226 miles (363.7 km)|
|Meets:||E05, E20, E15|
|Former Number(s):||E34, E114, E115|
|Route outline (key)|
In the British Isles
Starting at the port in Holyhead the E22 goes via Chester, Manchester, Leeds and Scunthorpe to Immingham and the port there. It multiplexes with the E05 at Warrington and the E20 from Warrington to Rawcliffe, meeting the E15 at Darrington, en route.
The E22 continues through the Netherlands, Germany, Sweden, Latvia, and Russia to an eastern terminus at Ishim in the Tyumen Oblast of western Siberia. The route's total length is around 5,320 km.
Holyhead • Bangor • Conwy • Chester • Runcorn • Warrington • Salford • Manchester • Rochdale • Huddersfield • Halifax • Bradford • Leeds • Wakefield • Pontefract • Goole • Doncaster • Scunthorpe • Immingham
In 1974, it was proposed that the E22 went via Sheffield, working in a world where the M67 was going to reach the M1, allowing a more direct route between Warrington and Doncaster via Stockport and the M67.